New Eye Treatment Effective for Macular Degeneration

A new treatment for the eye disease macular degeneration is showing great promise in studies. This may potentially lead to new forms of treatment for age-related macular degeneration and could help prevent blindness caused by this degenerative eye disease.

Research conducted at the Scripps Research Institute in California has produced great results for a new macular degeneration treatment. The study involves controlling actions of microRNAs once considered junk in genetic material. However, with research showing these tiny pieces of RNA fine-tune gene activation, research into treatments for macular degeneration has shown that it may be apposible to stop the neovascularization of blood vessels that causes wet macular degeneration.

Wet macular degeneration occurs when blood vessels ‘leak’ causing damage to the central vision in those people suffering from this form of AMD. The research conducted shows that when treating mice with microRNA it was possible block the growth of these ‘leaky’ blood vessels without causing damage. This made researchers conclude it may be possible to treat eye diseases such as macular degeneration.

Senior author of the story, Professor Martin Friedlander, MD, PhD stated “We believe that targeting and inhibiting the action of microRNAs involved represent a novel and effective way to treat a broad range of neovascular eye diseases such as diabetic retinopathy, macular degeneration and macular telangiectasia.”

Research into macular degeneration has shown that the eye disease is linked to a protein called VEGF. This causes abnormal growth of blood vessels in the back of the eye, affecting the retina and damaging central vision. This is common in wet macular degeneration and the rapid progression of the eye disease results in blindness in a majority of the aging population diagnosed with the condition. Until now, treatments has largely consisted of anti-VEGF injections of drugs such as Lucentis, Avastin, Macugen and Eylea.

These macular degeneration treatments blocked VEGF production and prevented the growth of abnormal blood vessels in the eye. Unfortunately, it could also disable growth of new vessels and affect the function of the nerve cells and blood vessels in the retina, creating unintended problems in the eye.

Utilizing treatments for macular degeneration designed around microRNA blocking could potentially revolutionize treatments for the eye disease.

Comments

  1. Darlene Munro says:

    My mom has dry macular and they basically told her to go home and get prepared for blindness, my mom is a retired nurse and is having a very hard time with this, if there is any chance at all of her getting some of her site back it would be great to know, also what needs to be done. Any information you can provide would be greatly appreciated, we are willing to try anything. Thank you

    • Cindy Penny says:

      My mom has dry macular as well and was basically told the same thing that nothing could be done for her. If there is any information that is to the contrary, I would love to know and are willing to try anything. Thank you.

      • Nettie Kokura says:

        I have dry MD. I tried to get into trials or whatever in order to prevent further degeneration in my eyes.
        The only thing I found that helped me is.micro acupuncture. I started getting micro acupuncture In 2012 and my acuity readings have improved. Prior to my first treatment I needed a magnifying glass all the time for normal things like paying bills. Today I am able to manage quite well with just my reading glasses. I started the treatments in the U.S. But now I get them in Burnaby, BC. At West Coast Micro Acupuncture. Details of my acuity readings can be seen at wcmacanada.com.

        I will continue to get micro Acupuncture treatments whenever I feel I need them until something more permanent is developed. The Micro acupuncture is not a cure,but it helps, and is all I can find until stem cells or something else is available. If enough people receiving the treatment could show improvement to their eye sight we aye able to convince Health Care to at least assist with the cost.

  2. I was diagnosed with macular degeneration in my left eye in 2014 . Was given prescription for Latanoprost 0.005% eye drops to use at bedtime . Don’t know how effective they are as my last three eye dr. appointments with Ochsner Clinic in Baton Rouge La. I wasn’t tested for it or told anything really but to come back in 3 mounths !

  3. SHARON WATSON says:

    My ophthalmologist told me that I needed cataract surgery in 2013, really all I wanted was prescription glasses. The first eye was done and the next day I felt the vision had deteriorated returned to the Dr. who said it was just swollen and that is why I could not see as well, this went on for two months finally was sent to a specialist diagnosed with wet macular degeneration and got monthly injections, now two years later, the blood vessel leaked Monday morning when I got up I had lost 70 percent vision in left eye. Got another injection Tuesday but no guarantee that vision will return. I am now the fifth case out of a small circle of people I know that had cataract surgery and then contacted wet macular degeneration. I am told that it would of happened anyway, but that the surgery speeds it up, I would like to know how fast it accelerates it had I even known there was a remote chance this would happen there is no way I would of gone ahead with cataract surgery, just because it is covered by the government, this same Dr. has made of 2.5 million from cataract surgery alone in 2014. Anyone have any idea how I could find stats on this. I was advised bvy another Dr. Class Action lawsuit

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