Fenretinide Slows Progression of Dry Macular Degeneration

Fenretinide has shown positive results for slowing the progression of dry macular degeneration in its Phase II trial.  Sirion Therapeutics announced the positive results after all patients participating in the trial had reached their 12 month visit.

Fenretinide is an oral vitamin A binding protein that has been used in patients with advanced dry macular degeneration.  It is believed that the accumulation of retinol or vitamin A toxins can be halted by Fenretinide, thus slowing the formation and accumulation of toxic by-products typically associated with dry macular degeneration.

Patients in the Phase II trial were either treated with a placebo or fenretinide.  Patients treated with 300 mg of oral fenretinide showed slower growth and slower progression of their dry macular degeneration, 22.7 percent versus 41.6 percent in the placebo growth.

Based on the results, Sirion plans to continue its study to its conclusion and will meet with its scientific advisors and FDA to design an an appropriate Phase III trial for fenretinide.

With the results of Fenretinide at slowing the progression of dry macular degeneration, this may offer hopes to those patients diagnosed with the eye disease.  Currently, there are few treatment options for dry macular degeneration.

Comments

  1. Peter Fischer says:

    Dear Ladies and Gentlemen,
    We have the following questions :
    1.) Is fenretinide approved by the FDA ??
    2.) is fenretinide now available to buy en US – Pharmacies ??
    3.) Where can we buy this medicine in Europe / Germany ??
    Thank you very much for your fine cooperation in this matter
    Best Regards – Peter Fischer – Mexico City

  2. I have the same questions as Peter Fisher. New York

  3. Bob Henry says:

    It seems we all have the same questions and no answeres. I could get no info from FDA or ReVision on Phase 3, when it will start of when it will end. I have called several pharmacies in Mexico and they haven’t heard of it. I don’t relish going blind while the wheels grind on. I’ll keep looking and post anything I find out. If you know anything more, my email is bobhenry@dc.rr.com
    Regards

  4. Barbara wright says:

    i welcome any information as to Dr. In Canada who could evaluate my graphic atrophy and possible prescribe fenretinide or any other possible drug

Trackbacks

  1. Fenretinide Slows Progression of Dry Macular Degeneration | Macular Degeneration Support Canada…

    Macular degeneration is the leading cause of blindness in people over the age of 50. Dry macular degeneration currently has little treatment options and a new treatment, Fenretinide, has been shown to be effective at slowing the progression of dry mac…

  2. Fenretinide Slows Progression of Dry Macular Degeneration | Macular Degeneration Support Canada…

    Dry macular degeneration has no real treatment options and with macular degeneration being the leading cause of blindness in people over the age of 50, having a new  treatment to slow the progression of the eye disease is big nows.  Fenretini…

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