Stem Cell Treatment for Macular Degeneration

January 27, 2009

A stem cell treatment for macular degeneration may be on the horizon.  British scientists have indicated they will seek approval to conduct human trials of an embryonic stem cell therapy for macular degeneration – the leading cause of vision loss in people aged 65 and older.

This announcement to seek approval comes shortly after the United States gave approval for human trials using embryonic stem cells.

According to Pete Coffey of the University College of London, the US decision to approve the trial using human stem cells to treat paralysis was great news, clearing the way for having the human stem cell treatment for macular degeneration approved.  “It clearly gives a lot of direction to our regulars.  It is a precedent of sorts,” Coffey had stated, when talking about the decision to seek approval for this macular degeneration stem cell treatment.

Coffey and his colleagues have already used embryonic stem cells to grow retinal pigment epithelium cells.  These are the cells that are destroyed when a person is diagnosed with having macular degeneration.  Using the developed stem cell therapy, Coffey has been able to show promise in reversing the damage caused by macular degeneration in animals.

Before this stem cell treatment for macular degeneration can be approved for human trials, Coffey and his colleagues must finalize the safety data.  Approval must be given from the Human Tissue Authority, the Medicines and Health Care products Regulatory Agency,and the Gene Therapy Advisory Committee before the macular degeneration stem cell therapy can be tested on humans.

During the initial stages of testing, the researchers have indicated they will be concentrating on the dry form of macular degeneration.  This form of the eye disease affects approximately 90 percent of the suffers and has no viable drug treatment and no cure.

This stem cell treatment for macular degeneration that is on the horizon should be seen by those people suffering from the disease as a major announcement.

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{ 27 comments… read them below or add one }

DIANNA May 3, 2009 at 7:46 pm

Have human trials already begun? My father would be interested…

lawrence phelan May 6, 2009 at 7:58 pm

I was diagnosed about 10 tears ago with dry Macular degeneration and this sounds, tome, like the answer we have been waiting for. I would certainly be intrested in joining a trial.

Edmond ALVES for Wife Dorlene May 31, 2009 at 7:07 pm

My wife was diagnosed 5 years ago, as have Macular Degeneration.. She
would love to be in any trial. She and I have been waiting for trials and 0r
treatments for this disease.

Herb Fuller June 25, 2009 at 4:02 pm

I have macular degeneration and it would be a god send if stem cell works.
I am interested.

Lisa Klewer July 15, 2009 at 4:02 am

My dad is 90 years old and suffers from age related dry macular degeneration. His health is good otherwise. Both his eyes are affected,
one worse then the other. He will be very happy to receive a promising
treatment. Travel is no object. Thankyou

GRACE ELWELL July 18, 2009 at 4:52 am

THREE YEARS AGO I WAS DIAGNOSED WITH MICREL DEGENERATION. I AM VERY INTERESTED IN STEN CELL RESEARCH .WHERE CAN I GET MORE IMFORNATION

GRACE ELWELL July 18, 2009 at 5:03 am

I WAS DIAGNOSED 3 YEARS AGO WITH MACULAR DEGERATION. I AM VERY INTERESTED IN THE STEM CELL RESERCH.

Joop Beunders August 20, 2009 at 6:53 am

I was diagnosed some 3 years ago with MD. I now found a place in Germany (Cologne) where there seems to be MD treatment based on stem cells on a “regular” basis. I’m 60 years of age and applied for treatment and am now waiting for the appointment.

adell taylor September 3, 2009 at 1:03 am

WHEN WILL STEM CELL TRIALS BE A IN THE U.S. ?

Raema September 9, 2009 at 9:32 pm

I have 22 year old son who is now legally blind due to macular vision loss. This treatment is vital and urgent

Derryl Johnston October 29, 2009 at 1:56 pm

I would like to be part of the trials.

Bill Rinella November 10, 2009 at 3:02 am

Bill just turned 65 and has been trying to slow the progression for the last 15 years. He gave up driving a year ago. We have our own business and what used to be a day’s work turns into 3 days. We checked into going to Germany to the Xcell Center, but through a few doctors guidance found there wasn’t any information on successes. I know we are not eligable for your trials, but would want to be contacted as soon as you have approval do treat.
Entered by his wife, Linda

MICHEL November 21, 2009 at 9:50 pm

43with 2 kids and a mortgage.
Recently diagnosed with dry MA .
Interested in clinical trail or info

Kind regards

Michael

MICHEL November 21, 2009 at 9:53 pm

Ooops wrong email address in last comment.
(I guess i have an excuse)

43with 2 kids and a mortgage.
Recently diagnosed with dry MA .
Interested in clinical trail or info

Kind regards

Michael

Janice Newton November 25, 2009 at 11:13 pm

I have dry macular degeneration , mostly in my left eye. My twin sister has wet degeneration. I am 74 years old and hate the thought I might not be able to drive for very long. Would love to be in a clinical trial progam.
Janice

Janice Newton November 25, 2009 at 11:24 pm

aaaaaaaaaaaaaai have dry macular degeneration mostly in my left eye. My twin sister has the wet type. I am 74 and very active and hate the thought that I may not be able to drive soon.I live alone and still work part time at the local Walmart. Would very much like to br considered for a trial program. Thank you , Janice

Vicky Guest December 9, 2009 at 5:44 pm

My Mum has recently been diagnosed with dry macular degeneration in both eyes. she would really like to be involved in any stem cell trials and have more information.
Thanks Vicky

diana December 20, 2009 at 10:10 pm

my father has dry macular degeneration , please let us know when the
clinical trial will start.
the family is very concern because he is taking care of our mother and she has alzheimer ,he is in charge of her medicines.
Please let us know of any information that can possibly make a change in my father’s vision
thanks,
diana

Rana Aransa February 9, 2010 at 4:12 pm

my cousin has the wet MD and we would like to know how we could involve him in the trial?
he lives in egypt and we dont mind going anywhere in the world for him to get treated. he is 38 years old.

Herb Fuller February 24, 2010 at 10:19 pm

I am looking for macular degeneration stem cell treatment for my eyes. I am ready before I get any older.

Chetan April 6, 2010 at 6:58 pm

Hi,

My mother has macular degeneration along withb high myopia. She will be very interested in stem cell therapy. Please let us know if she can be past of the trials.
Thanks

michelle April 10, 2010 at 11:48 pm

I have multiple sclerosis it seems to be moving rapidly i livein pain, 95% ofmy energy is gone
i was taking avonex for 1 year but its not working anymore for me
i would like to have the stem cell treatment done
i have the stem cells the cord blood stored because my daughter had her baby in dec 09
is there anywhere in canada i can go to get this treatment done
please let me know asap because i,m going down really fast
thanks
michelle

rachel Kanno April 12, 2010 at 3:35 am

I have been diagnosed with Macular degeneration (dry) 3 months ago. I am 61 years old and very much interested in a treatment plan. I have been communicating with a doctor in Germany and awaiting an answer. I would like to know if I can be treated via stem cell or any other FDA approved treatment. Please contact me at rdkanno@aol.com. My contact is (209) 996-1552 or (209) 577-1998.

Thanks,
Rachel

Kim April 18, 2010 at 1:47 am

My father has been diagnosed with dry AMD. He is an intellectual and reads several papers a day etc. This has been devastating as he is in excellent health otherwise. Please let us know about trials – travel etc not an issue.

Many thanks.

David Dixon June 17, 2010 at 6:23 am

My father has the dry type. He would love to take part in any trial that would improve things for him for the time he has left. Please let us know when / if anything is possible.

Virgie Parks July 10, 2010 at 11:35 pm

Please notify me when I can receive treatment, on a trial basis or once it is passed by fda for regular treatment. Thank you

marisela black July 26, 2010 at 9:18 pm

I have been a patient at UCLA eye clinic for the past 20 plus years. Its a great program and I hope this new treatment will work for all of us that are loseing our sight. Please keep me posted

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